About P N Lee Statistics and Computing Ltd

We offer expert advice on statistical and computing issues and our well
qualified staff have a wealth of experience including:-

Latest News: In August 2010 PNLSC were accepted as a member of the UK Good Laboratory Practice Compliance Monitoring Programme by MHRA

Epidemiology

• The statisticians at P N Lee Statistics and Computing Ltd (PNLSC) have extensive experience in the design, conduct and analysis of epidemiological studies and have published papers on subjects as diverse as asbestos, asthma, large bowel cancer, passive smoking, heart disease and vitamin A, working closely with medical experts.
• Many critical assessments of key epidemiological papers and reviews of epidemiological evidence on specific issues have been carried out.

Toxicology

• Peter Lee is co-author of the two IARC monographs on design and analysis of long term carcinogenicity studies and, with John Fry, has written a number of papers on the subject.
• Peter Lee and his colleagues have conducted detailed interpretative statistical analyses of histopathological and other data from numerous studies for many major companies, both as the primary investigation and as a second opinion on key issues.
• We also have extensive experience in analysis of general in-life toxicological data, and data from toxicokinetic, reproductive and photocarcinogenicity  studies
• In August 2010 PNLSC were accepted as a member of the UK Good Laboratory Practice Compliance Monitoring Programme by MHRA. We can therefore now provide statistical analyses of all aspects of toxicological data under a GLP environment.
• We also develop and market RoeLee software for analysis of carcinogenicity studies

Clinical Trials

Having been involved in clinical trials for many companies PNLSC have amassed  considerable experience in this area. As such we can offer many services to assist your clinical trial:

• Sample size estimation.
• Assistance in protocol development and design of case report forms.
• Setting up the database.
• Double data entry.
• Data error detection and resolution.
• Statistical analysis of data.
• Assistance in preparing final report and paper for publication.

Software

The developers at PNLSC produce bespoke software systems tailored for client specific applications

• RoeLee.
• Peer Review.

We also develop database systems using Excel, VBA and SAS such as :-

• RR Estimation:   A relative risk estimation system.
• IMASS:   International Mortality and Smoking Statistics.